Exercise induced Rhabdomyolysis
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.I am 38 years old and am in the process of going through blood tests and muscle biopsies to test whether I have a metabolic disorder called CPT2. This disorder was suspected as I went though a bad bout of rhabdomyolysis in early June (was hospitalised for 2 weeks) - with severe pain in both quadriceps, and CK levels close to 7000. Within 2 weeks CK levels were back down to normal, but I still have ongoing muscle twitches and pain.
Prior to this rhabdo episode I had increased my exercise regime quite signicantly. I started to cycle to work (25kms each way) 3-4 times per week - I had reached a decent level of fitness before I started this, but cycling to and from work was quite a big jump (I was also leaving the house at 6.15am each morning, without food, only water). 1 week before the rhabdo I stopped the cycling due to some back twinges, and a suspected stomach virus.
My question is:
I was wondering if anyone has come across other cases of rhabdo that occur 1 week or more after finishing strenuous exercise - or do all cases of exercise-induced rhabdo occur within a few minutes/hours of such exercise? After several different tests for metabolic disorders have come out inconclusive, I am wondering whether I just "over did" it - and the combination of poor diet management, strenuous exercise whilst not fit enough and over-heating may have set off the rhabdo.
Also, does anyone know how quickly people recover from rhabdo episodes - and how soon are they able to get back to "normal" levels of exercise?
Regards
Andy




Exercise induced Rhabdomyolysis
29th Nov '09, 1:25pm
I think you have overdone it, for which I am a veteran of. I have been getting exercise induced rhabdomyolysis for 15 years before I realised what was going on. Similar story: cyclist only get it in thighs severe cramps especially when not riding eg days off. Unfortunately live next to a mountain. Train 4 x/week, hopeless diet probably low in everything:sodium,potassium,calcium, too much caffeine, always dehydrated, not enough protein,too much wine. Had a lot of metabolic tests including muscle biopsy, electron micrographs,McArdle gene testing,fatty acid oxidation deficiencies etc..all negative. Get severe cramps only occasionally when exercising (if so get off bike and stretch few minutes), but often days when I am resting or do other exercise eg running, walking. Get severe rhabdomyolysis once/yr only hospitalised x 1. No kidney effects. Can't ride or walk. It takes 3 weeks to recover from,almost to the day. Be keen to talk to any others with problem. Currently taking lots of supplements and am going to give up caffeine, not sure about the wine though.